Audrey Grant PhD

Audrey Grant is an Assistant Professor in the Department of Anesthesia. She has applied her expertise in Genetic Epidemiology and Statistical Genomics to the study of immunological traits and diseases, and more recently, to pain, especially the development of chronic pain. Currently, her laboratory conducts genome wide association (GWA) studies using large, publicly available clinical databases including the UK Biobank (UKB) and the Canadian Longitudinal Study on Aging, applying classical and new machine-learning approaches in combining GWAS test statistics with data from other tissue-specific expression or epigenetics sources, towards an integrative genomics to characterize the genetic architecture of pain phenotypes, and to parse environmental from genetic etiological components. The goal is to glean new insights on the pathophysiological implications of the underlying genetic architecture for downstream clinical intervention.